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A system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principal Component BiSulfite, 'PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: <https://katlande.github.io/PCBS/articles/Differential_Methylation.html>.
Package details |
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Author | Kathryn Lande [aut, cre, cph] |
Maintainer | Kathryn Lande <kathryn.lande@mail.mcgill.ca> |
License | GPL-3 |
Version | 0.1.1 |
URL | https://github.com/katlande/PCBS |
Package repository | View on CRAN |
Installation |
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