calculate_parameters: Calculate model-specific variables using a dummy call to...

In PKPDsim: Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Calculate model-specific variables using a dummy call to sim_ode()

Description

This is a convenience function for PKPDsim users, it is not used inside the 'sim_ode()“ function in any way. This function is useful for converting from an estimated parameter to actual parameter, e.g. when clearance is specified as 'CLi = CL * (WT/70) * (1/CR)' it can be used to calculate 'CLi' without having to write that function a second time in R.

Usage

calculate_parameters(
  ode = NULL,
  parameters = NULL,
  covariates = NULL,
  include_parameters = TRUE,
  include_variables = TRUE,
  ...
)

Arguments

ode	PKPDsim model object
parameters	parameter list
covariates	covariate list. Make sure to include covariates at the right time point, since only last observed covariate values are used.
include_parameters	boolean, include parameters?
include_variables	boolean, include variables?
...	arguments to pass on to simulation function

Value

List of model-specific variables

PKPDsim documentation built on March 7, 2023, 5:40 p.m.