Estimation of the variance components under the null model using the ASKAT method

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Description

Estimation of the variance components under the null model using the ASKAT method

Usage

1
Estim.H0.ASKAT(y, X, S, U)

Arguments

y

Vector of phenotype values

X

A matrix of covariates, including intercept.

S

Matrix obtained from spectral decomposition of the relationship matrix: Φ = U S U^T.

U

Matrix obtained from spectral decomposition of the relationship matrix: Φ = U S U^T.

Value

A vector with the following values:

  • s.e: variance component due to the error term (residuals)

  • s.g: variance component due to the polygenic residual (polygenic background)

  • beta: the estimate of the effects of the covariate (if there are some in the data)

Author(s)

Karim Oualkacha

M'Hamed Lajmi Lakhal-Chaieb

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