pvalue.ASKAT: Compute p-value and score for the ASKAT method

In RVPedigree: Methods for Family-Based Rare-Variant Genetic Association Tests

Description

Compute p-value and score for the ASKAT method

Usage

pvalue.ASKAT(RH0, y, X, Phi, W, G)

Arguments

RH0	a vector of length 2 which the results (output) of the Estim.H0.ASKAT function (i.e. variance components estimates under the null model)
y	vector of phenotype data (one entry per individual), of length n.
X	matrix of covariates including intercept (dimension: n \times p, with p the number of covariates)
Phi	Relationship matrix (i.e. twice the kinship matrix); an n \times n square symmetric positive-definite matrix.
G	matrix of genotypes

Value

A list with score and p-value for the ASKAT test on the given data. The list contains the elements score and p.value.

Author(s)

Karim Oualkacha

RVPedigree documentation built on May 29, 2017, 10:19 p.m.