# pvalue.NormalizedASKAT: Compute p-value and score for the normalized ASKAT method In RVPedigree: Methods for Family-Based Rare-Variant Genetic Association Tests

## Description

Compute p-value and score for the normalized ASKAT method

## Usage

 1 pvalue.NormalizedASKAT(RH0, y, X, Phi, W, G) 

## Arguments

 RH0 a vector of length 2 which the results (output) of the Estim.H0.ASKAT function (i.e. variance components estimates under the null model) y vector of phenotype data (one entry per individual), of length n. X matrix of covariates including intercept (dimension: n \times p, with p the number of covariates) Phi Relationship matrix (i.e. twice the kinship matrix); an n \times n square symmetric positive-definite matrix. G matrix of genotypes

## Value

A list with score and p-value for the Normalized ASKAT test on the given data. The list contains the elements score and p.value

## Author(s)

Karim Oualkacha

RVPedigree documentation built on May 29, 2017, 10:19 p.m.