Description Usage Arguments Value Author(s) References See Also Examples

The *p x p* target G is computed from the
*n x p* data matrix.
It is defined as follows (*i,j = 1,...,p*):

*sii if i=j ; r√{s_{ii}s_{jj}} if i~j ; 0 otherwise *

where *r*
is the average of sample correlations and *sij* denotes the entry of
the unbiased covariance matrix in row *i*, column *j*. The
notation *i ~ j* means that genes
*i* and *j* are connected, i.e. genes *i* and *j*
are in the same gene functional group.

1 | ```
targetG(x, genegroups)
``` |

`x` |
A |

`genegroups` |
A list of genes obtained using the database KEGG, where each entry itself is a list of pathway names this genes belongs to. If a gene does not belong to any gene functional group, the entry is NA. |

A *p x p* matrix.

Monika Jelizarow and Vincent Guillemot

J. Schaefer and K. Strimmer, 2005. A shrinkage approach to large-scale covariance matrix estimation and implications for functional genomics. Statist. Appl. Genet. Mol. Biol. 4:32.

M. Jelizarow, V. Guillemot, A. Tenenhaus, K. Strimmer, A.-L. Boulesteix, 2010. Over-optimism in bioinformatics: an illustration. Bioinformatics. Accepted.

`targetCor`

,
`targetF`

,
`targetG`

,
`targetGstar`

,
`targetGpos`

.

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