feature_coexp: feature_coexp

In SiFINeT: Single Cell Feature Identification with Network Topology

feature_coexp

Description

The function calculates coexpression patterns between genes

Usage

feature_coexp(so)

Arguments

so	a SiFINeT object

Details

The coexpression pattern of a pair of genes is a normalized co-occurrence of high (or equivalently low) expression level of the 2 genes in the classified count matrix. The normalization is based on the estimated quantiles of the low-high separation instead of the quantiles used for quantile regressions. Theoretically, the distribution of coexpression patterns should asymptotically follow standard Gaussian distribution if at least one of the 2 genes is not differentially expressed feature gene.

Value

SiFINeT object with coexp (gene coexpression matrix) updated.

SiFINeT documentation built on April 3, 2025, 9:30 p.m.