SimEvolEnzCons: Simulation of Evolution of Enzyme Under Constraints

Simulate the evolution of enzyme concentrations under selection for increased flux in a metabolic pathway, with cellular constraints. Create graphics for the simulation results. Compute evolutionary equilibrium and Range of Neutral Variations of enzyme concentrations. This package is part of "Coton, C., Talbot, G., Le Louarn, M., Dillmann, C., de Vienne, D. (2021) <bioRxiv:10.1101/2021.05.04.442631>". Version 2.0.0 and more takes account of regulation groups, and is part of a second article "Coton, C., Dillmann, C., de Vienne, D. (in progress)".

Getting started

Package details

AuthorCharlotte Coton [aut, cre] (<>), Gregoire Talbot [aut], Maud Le Louarn [aut], Christine Dillmann [aut, ths] (<>), Dominique de Vienne [aut, ths] (<>)
MaintainerCharlotte Coton <>
LicenseGPL (>= 3)
Package repositoryView on CRAN
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SimEvolEnzCons documentation built on Oct. 29, 2021, 1:07 a.m.