odd.discrete.sel.coef: Equation of null coefficient selection
In SimEvolEnzCons: Simulation of Evolution of Enzyme Under Constraints

Description Usage Arguments Details Value See Also

(Utilitary function). Gives the result of the equation corresponding to discrete coefficient selection and indirect mutation of E

1	odd.discrete.sel.coef(delta_fun,i_fun,E_res,A_fun,alpha_fun,sel_coef_fun)

`delta_fun`	Numeric value of the actual effect of a mutation targeting enzyme `i_fun`, i.e. δ_i
`i_fun`	Integer number indicating the enzyme targeted by the mutation
`E_res`	Numeric vector of resident enzyme concentrations
`A_fun`	Numeric vector of activities
`alpha_fun`	Numeric matrix of redistribution coefficients
`sel_coef_fun`	Numeric value of selection coefficient

Gives the result of the equation corresponding to discrete coefficient selection and indirect mutation of E. Corresponding equation is ∑ ( \frac{1}{A_j E_j} (\frac{1}{1 + s} - \frac{E_j}{E_j + α_{ij} δ_i} ) )

Null this equation corresponds to search the δ_i corresponding to the given resident concentrations and selection coefficient.

This function is used to find δ at bounds of the Range of Neutral Variation, where selection coefficient s is equal to +/-1/N.

A numeric value

See function alpha_ij to compute the redistribution coefficients.

SimEvolEnzCons documentation built on Oct. 29, 2021, 1:07 a.m.