AdjStats | R Documentation |
Produce the prior structure-adjusted statistic.
AdjStats(y, V, k, mu, fudge=0.005)
y |
a vector or a matrix of unadjusted z-values |
V |
a correlation matrix defined based on the prior structure |
k |
a numeric value representing the ratio of variance components |
mu |
a numeric value of the mean of the prior distribution |
fudge |
a small numeric value added to the diagonal of the correlation matrix to improve stability |
a vector or a matrix of adjusted z-values
Jun Chen
Xiao, J., Cao, H., Chen, J. (2017). False discovery rate control incorporating phylogenetic tree increases detection power in microbiome-wide multiple testing. Bioinformatics, 33(18), 2873-2881.
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