TRD: Transmission Ratio Distortion

Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.

Package details

AuthorLam Opal Huang
MaintainerLam Opal Huang <opal.huang@mail.mcgill.ca>
LicenseGPL (>= 2)
Version1.1
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("TRD")

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TRD documentation built on May 2, 2019, 5:12 a.m.