bcrm: Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

Implements a wide variety of one and two-parameter Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics.

Author
Michael Sweeting
Date of publication
2015-11-20 18:07:59
Maintainer
Michael Sweeting <mjs212@medschl.cam.ac.uk>
License
GPL (>= 2)
Version
0.4.6

View on CRAN

Man pages

bcrm
Bayesian Continual Reassessment Method for Phase I...
bcrm-package
Bayesian Continual Reassessment Method for Phase I...
find.x
Obtain samples from the maximum tolerated dose (MTD)...
getprior
Samples from the specified prior distribution.
plot.bcrm
Plot the estimated dose-toxicity curve
plot.bcrm.sim
Plot the operating characteristics from the simulated trials
plot.threep3
Plot the operating characteristics from a standard 3+3 trial
posterior
Calculate posterior distribution of CRM model parameter(s)
print.bcrm
Print information regarding a trial conducted using the...
print.threep3
Print information regarding the operating characteristics of...
threep3
Calculate all possible trial pathways for the standard 3+3...

Files in this package

bcrm
bcrm/inst
bcrm/inst/CITATION
bcrm/NAMESPACE
bcrm/NEWS
bcrm/R
bcrm/R/bcrm_0.4.6.R
bcrm/MD5
bcrm/DESCRIPTION
bcrm/man
bcrm/man/plot.threep3.Rd
bcrm/man/find.x.Rd
bcrm/man/bcrm-package.Rd
bcrm/man/threep3.Rd
bcrm/man/bcrm.Rd
bcrm/man/plot.bcrm.Rd
bcrm/man/getprior.Rd
bcrm/man/plot.bcrm.sim.Rd
bcrm/man/posterior.Rd
bcrm/man/print.threep3.Rd
bcrm/man/print.bcrm.Rd