# Plot the estimated dose-toxicity curve

### Description

The estimated dose-toxicity curve using the Bayesian continuous reassessment method is plotted for the patients thus far recruited into the trial

### Usage

1 2 |

### Arguments

`x` |
An object of class "bcrm", as returned by |

`each` |
Should posterior summaries be plotted after each recruited cohort? Defaults to FALSE. |

`trajectory` |
Should the sequential dose trajectory of the recruited patients be plotted, along with the observed toxicities? Defaults to FALSE. |

`file` |
File name where the dose-response plots are stored, in a pdf format. The program will ammend the current sample size to the end of the file name. |

`...` |
Further arguments passed to or from other methods |

### Details

The estimated 2.5%, 25%, 50%, 75%, 97.5% quantiles of the probability of toxicity are plotted for each dose. Additionally, a histogram of the number of toxicities and non-toxicities is plotted at each experimented dose.

If `trajectory = TRUE`

then the sequential dose trajectory and observed toxicities are plotted.

### Author(s)

Michael Sweeting mjs212@medschl.cam.ac.uk (University of Cambridge, UK)

### References

Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. *Journal of Statistical Software* (2013) 54: 1–26.
http://www.jstatsoft.org/article/view/v054i13

### See Also

`bcrm`