Description Usage Arguments Details Author(s) References See Also

Plots of the operating characteristics obtained from a CRM simulation.

1 2 |

`x` |
An object of class "bcrm.sim", as returned by |

`trajectories` |
Should a summary plot of the trajectories of administered dose levels be plotted? Defaults to FALSE. |

`file` |
File name where the operating characteristic plot is stored, in a pdf format. |

`threep3` |
Should operating characteristics of a standard 3+3 rule-based design be plotted alongside the |

`...` |
Further arguments passed to or from other methods |

This function plots the sample size distribution (if variable), the experimentation distribution, the recommended dose distribution and the percentage of subjects who experience the toxicity outcome (dose-limiting toxicity).
If `trajectories = TRUE`

then summary statistics of administered dose levels for each patient are plotted instead.
If `threep3 = TRUE`

then the operating characteristics of the standard 3+3 design are plotted alongside those of the `bcrm`

design (see `threep3`

for more details).

Michael Sweeting [email protected] (University of Cambridge, UK)

Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. *Journal of Statistical Software* (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13

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