# Plot the operating characteristics from the simulated trials

### Description

Plots of the operating characteristics obtained from a CRM simulation.

### Usage

1 2 |

### Arguments

`x` |
An object of class "bcrm.sim", as returned by |

`trajectories` |
Should a summary plot of the trajectories of administered dose levels be plotted? Defaults to FALSE. |

`file` |
File name where the operating characteristic plot is stored, in a pdf format. |

`threep3` |
Should operating characteristics of a standard 3+3 rule-based design be plotted alongside the |

`...` |
Further arguments passed to or from other methods |

### Details

This function plots the sample size distribution (if variable), the experimentation distribution, the recommended dose distribution and the percentage of subjects who experience the toxicity outcome (dose-limiting toxicity).
If `trajectories = TRUE`

then summary statistics of administered dose levels for each patient are plotted instead.
If `threep3 = TRUE`

then the operating characteristics of the standard 3+3 design are plotted alongside those of the `bcrm`

design (see `threep3`

for more details).

### Author(s)

Michael Sweeting mjs212@medschl.cam.ac.uk (University of Cambridge, UK)

### References

Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. *Journal of Statistical Software* (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13

### See Also

`print.bcrm.sim`

, `bcrm`

, `threep3`