plot.bcrm.sim: Plot the operating characteristics from the simulated trials
In bcrm: Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

Description Usage Arguments Details Author(s) References See Also

Plots of the operating characteristics obtained from a CRM simulation.

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## S3 method for class 'bcrm.sim'
plot(x, trajectories = FALSE, file = NULL,
  threep3 = FALSE, ...)

`x`	An object of class "bcrm.sim", as returned by `bcrm` when conducting a simulation.
`trajectories`	Should a summary plot of the trajectories of administered dose levels be plotted? Defaults to FALSE.
`file`	File name where the operating characteristic plot is stored, in a pdf format.
`threep3`	Should operating characteristics of a standard 3+3 rule-based design be plotted alongside the `bcrm` design? Defaults to `FALSE`.
`...`	Further arguments passed to or from other methods

This function plots the sample size distribution (if variable), the experimentation distribution, the recommended dose distribution and the percentage of subjects who experience the toxicity outcome (dose-limiting toxicity). If trajectories = TRUE then summary statistics of administered dose levels for each patient are plotted instead. If threep3 = TRUE then the operating characteristics of the standard 3+3 design are plotted alongside those of the bcrm design (see threep3 for more details).

Michael Sweeting mjs212@medschl.cam.ac.uk (University of Cambridge, UK)

Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13

print.bcrm.sim, bcrm, threep3

bcrm documentation built on Aug. 23, 2019, 5:05 p.m.