Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials


Implements a wide variety of Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics.


Package: bcrm
Type: Package
Version: 0.4.6
Date: 2015-11-20
License: GPL (>= 2)
LazyLoad: yes


Michael Sweeting

Graham Wheeler

Maintainer: Michael Sweeting


Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1–26.

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