Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

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Description

Implements a wide variety of Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics.

Details

Package: bcrm
Type: Package
Version: 0.4.6
Date: 2015-11-20
License: GPL (>= 2)
LazyLoad: yes

Author(s)

Michael Sweeting mjs212@medschl.cam.ac.uk

Graham Wheeler graham.wheeler@mrc-bsu.cam.ac.uk

Maintainer: Michael Sweeting mjs212@medschl.cam.ac.uk

References

Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13