Description Usage Arguments Details Author(s) References See Also

Print method for a 3+3 design specified using a `threep3`

.

1 2 |

`x` |
An object of class "threep3" as returned by |

`tox.cutpoints` |
An optional argument passed to |

`dose` |
Optional vector of length |

`...` |
Further arguments passed to or from other methods |

The following operating characteristics are printed for the standard 3+3 design:

- Sample size
Mean, minimum and maximum sample size of the design

- Experimentation proportion
Proportion of patients recruited to each dose, and to each true region of toxicity, on average

- Recommendation proportion
Proportion of 3+3 trials that would recommend each of the dose levels as the final maximum tolerated dose (see

`threep3`

for definition of the MTD), and the associated regions of true toxicity for the recommended MTDs- Average number of patients
The average number of patients dosed at each level

- Average number of DLTs
The average number of DLTs seen at each level

Michael Sweeting [email protected] (University of Cambridge, UK)

Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. *Journal of Statistical Software* (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13

bcrm documentation built on Jan. 29, 2018, 1:05 a.m.

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