Print method for a 3+3 design specified using a threep3
.
1 2 |
x |
An object of class "threep3" as returned by |
tox.cutpoints |
An optional argument passed to |
dose |
Optional vector of length |
... |
Further arguments passed to or from other methods |
The following operating characteristics are printed for the standard 3+3 design:
Mean, minimum and maximum sample size of the design
Proportion of patients recruited to each dose, and to each true region of toxicity, on average
Proportion of 3+3 trials that would recommend each of the dose levels as the final maximum tolerated dose (see threep3
for definition of the MTD), and the associated regions of true toxicity for the recommended MTDs
The average number of patients dosed at each level
The average number of DLTs seen at each level
Michael Sweeting mjs212@medschl.cam.ac.uk (University of Cambridge, UK)
Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13
threep3
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