fillIOVOccColumns: Fill IOV/Occasion columns.

In campsis: Generic PK/PD Simulation Platform CAMPSIS

Fill IOV/Occasion columns.

Description

Problem in RxODE (LOCF mode) / mrgsolve (LOCF mode), if 2 rows have the same time (often: OBS then DOSE), first row covariate value is taken! Workaround: identify these rows (group by ID and TIME) and apply a fill in the UP direction.

Usage

fillIOVOccColumns(table, columnNames, downDirectionFirst)

Arguments

table	current table
columnNames	the column names to fill
downDirectionFirst	TRUE: first fill down then fill up (by ID & TIME). FALSE: First fill up (by ID & TIME), then fill down

Value

2-dimensional dataset

campsis documentation built on Sept. 11, 2024, 7:18 p.m.