plot.emaxsim: Plot the output of emaxsim

In clinDR: Simulation and Analysis Tools for Clinical Dose Response Modeling

Plot the output of emaxsim

Description

A Q-Q plot of the dose response estimate of the mean at a specified dose minus the population value divided by the standard error of the estimator (computed using the delta method). Estimates based on alternative models when the Emax estimation fails are highlighted in red.

Usage

## S3 method for class 'emaxsim'
plot(x, id = x$idmax, plotDif= TRUE, ...)

Arguments

x	Output of emaxsim
id	Index of the dose to be assessed (placebo index=1).
plotDif	If true (default), the estimates and population values are differences with placebo. IF false, absolute dose response values are used.
...	Optional parameters passed to the plotting function

Value

No output is returned.

Author(s)

Neal Thomas

See Also

emaxsim, print.emaxsim, summary.emaxsim

Examples

## Not run: 
nsim<-50
idmax<-5
doselev<-c(0,5,25,50,100)
n<-c(78,81,81,81,77)

### population parameters for simulation
e0<-2.465375 
ed50<-67.481113 

dtarget<-100
diftarget<-9.032497
emax<-solveEmax(diftarget,dtarget,log(ed50),1,e0)

sdy<-7.967897
pop.parm<-c(log(ed50),emax,e0)    
meanlev<-emaxfun(doselev,pop.parm)  

###FixedMean is specialized constructor function for emaxsim
gen.parm<-FixedMean(n,doselev,meanlev,sdy)  
D1 <- emaxsim(nsim,gen.parm)

plot(D1,id=3)

## End(Not run)

clinDR documentation built on Aug. 9, 2023, 9:08 a.m.