StoppingGstarCIRatio-class: Stop based on a target ratio, the ratio of the upper to the...

In crmPack: Object-Oriented Implementation of CRM Designs

Stop based on a target ratio, the ratio of the upper to the lower 95% credibility interval of the estimate of the minimum of the dose which gives the maximum gain (Gstar) and the TD end of trial, the dose with probability of DLE equals to the target probability of DLE used at the end of a trial.

Description

Stop based on a target ratio, the ratio of the upper to the lower 95% credibility interval of the estimate of the minimum of the dose which gives the maximum gain (Gstar) and the TD end of trial, the dose with probability of DLE equals to the target probability of DLE used at the end of a trial.

Slots

targetRatio

the target ratio of the upper to the lower of the 95% credibility interval of the estimate that required to stop a trial

targetEndOfTrial

the target probability of DLE to be used at the end of a trial

Examples

##Define the target stopping ratio of 5 and 
##the target probability of DLE to be used at the end of a trial
##This is a ratio of the upper to the lower 95% credibility interval of the estimates
myStopping <- StoppingGstarCIRatio(targetRatio=5,
                                   targetEndOfTrial=0.3)

crmPack documentation built on Sept. 3, 2022, 1:05 a.m.