Stop based on probability of target biomarker

`target`

the biomarker target range, that needs to be reached. For example, (0.8, 1.0) and

`scale="relative"`

means we target a dose with at least 80% of maximum biomarker level.`scale`

either

`relative`

(default, then the`target`

is interpreted relative to the maximum, so must be a probability range) or`absolute`

(then the`target`

is interpreted as absolute biomarker range)`prob`

required target probability for reaching sufficient precision

1 2 3 4 5 6 7 | ```
# As example, here is the rule for:
# stopping the study if there is at least 0.5 probability that the biomarker
# (efficacy) is within the biomarker target range of [0.9, 1.0] (relative to the
# maximum for the biomarker).
myStopping <- StoppingTargetBiomarker(target = c(0.9, 1),
prob = 0.5)
``` |

crmPack documentation built on May 30, 2017, 4:42 a.m.

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