minSize: "MIN" combination of cohort size rules

minSizeR Documentation

"MIN" combination of cohort size rules

Description

This function combines cohort size rules by taking the minimum of all sizes.

Usage

minSize(...)

## S4 method for signature 'CohortSize'
minSize(...)

Arguments

...

Objects of class CohortSize

Value

the combination as an object of class CohortSizeMin

Functions

  • minSize(CohortSize): The method combining cohort size rules by taking minimum

See Also

maxSize

Examples


# Here is the rule for: 
#   having cohort of size 1 for doses <30
#   and having cohort of size 3 for doses >=30
mySize1 <- CohortSizeRange(intervals = c(0, 30),
                           cohortSize = c(1, 3))

# Here is the rule for: 
#   having cohort of size 1 until no DLT were observed
#   and having cohort of size 3 as soon as 1 DLT is observed
mySize2 <- CohortSizeDLT(DLTintervals=c(0, 1),
                         cohortSize=c(1, 3))

# This is combining the two rules above by taking the minimum of the sample sizes of
# the single rules
mySize <- minSize(mySize1, mySize2)


crmPack documentation built on Sept. 3, 2022, 1:05 a.m.