dip1: Dissolution data of a reference and a test batch

In disprofas: Non-Parametric Dissolution Profile Analysis

Description

A data set containing the dissolution data of one reference batch and one test batch of n = 6 tablets each, i.e. the dissolution profiles of the % drug release observed within a period of 120 minutes.

Usage

data(dip1)

Format

A data frame with 12 observations and 10 variables:

type

Factor with levels R (Reference) and T (Test)

tablet

Factor with levels 1 to 6 representing individual tablets

t.5

Numeric of the % release at the 5 minutes testing point

t.10

Numeric of the % release at the 10 minutes testing point

t.15

Numeric of the % release at the 15 minutes testing point

t.20

Numeric of the % release at the 20 minutes testing point

t.30

Numeric of the % release at the 30 minutes testing point

t.60

Numeric of the % release at the 60 minutes testing point

t.90

Numeric of the % release at the 90 minutes testing point

t.120

Numeric of the % release at the 120 minutes testing point

Source

See reference: Example data set shown in Table 1.

References

Tsong, Y., Hammerstrom, T., Sathe, P.M., and Shah, V.P. Statistical assessment of mean differences between two dissolution data sets. Drug Inf J. 1996; 30: 1105-1112.
doi: 10.1177/009286159603000427

Examples

str(dip1)

disprofas documentation built on Dec. 8, 2021, 5:10 p.m.