Description Usage Format Source References Examples
A data set containing the dissolution data of one reference batch and five test batches of n = 12 tablets each, i.e. the dissolution profiles of the % drug release observed within a period of 180 minutes.
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A data frame with 72 observations and 8 variables:
Factor with levels Reference
and Test
Factor with levels 1
to 12
representing
individual tablets
Factor with levels b0
, b1
, b2
, b3
,
b4
and b5
Numeric of the % release at the initial testing point
Numeric of the % release at the 30 minutes testing point
Numeric of the % release at the 60 minutes testing point
Numeric of the % release at the 90 minutes testing point
Numeric of the % release at the 180 minutes testing point
See reference: Example data set shown in Table 4.
Shah, V. P., Tsong, Y., Sathe, P., and Liu, J. P. In vitro dissolution
profile comparison - statistics and analysis of the similarity factor,
f_2. Pharm Res. 1998; 15(6): 889-896.
doi: 10.1023/A:1011976615750
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