dip4: Dissolution data of two different formulations

In disprofas: Non-Parametric Dissolution Profile Analysis

Dissolution data of two different formulations

Description

A data set containing the dissolution data of one reference batch and one test batch of n = 12 items each, i.e. the dissolution profiles of the % drug release observed at 10, 20 and 30 minutes.

Usage

data(dip4)

Format

A data frame with 24 observations and 2 variables:

type

Factor with levels ref (Reference) and test (Test)

x.10

Numeric of the % release at the 10 minutes testing point

x.20

Numeric of the % release at the 20 minutes testing point

x.30

Numeric of the % release at the 30 minutes testing point

Source

See reference: Example data set underlying Figure 1. Data set ‘ex_data_pharmind’ from package ‘T2EQ’.

References

Hoffelder, T. Highly variable dissolution profiles. Comparison of T^2-test for equivalence and f_2 based methods. Pharm Ind. 2016; 78(4): 587-592.
https://www.ecv.de/suse_item.php?suseId=Z|pi|8430

Examples

str(dip4)

if (requireNamespace("T2EQ")) {
library(T2EQ)

  data(ex_data_pharmind, envir = environment())
  str(ex_data_pharmind)
  rm(ex_data_pharmind)
}

disprofas documentation built on April 3, 2025, 5:48 p.m.