IM1xVibrio: Dose-Response data for 1-methyl-3-alkylimidazolium...

In drfit: Dose-Response Data Evaluation

Description

This is the raw data documenting the influence of the alkyl chain length in 3 position on the toxicity to the marine luminescent bacteria V. fischeri. The substances are named according to the UFT naming scheme of these substances. IM13 BF4 means 1-methyl-3-propylimidazolium tetrafluoroborate, IM14 BF4 means 1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10 BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.

Usage

data(IM1xVibrio)

Format

A dataframe containing the data as required for the drfit function. Additional columns contain the species tested (luminescent bacteria Vibrio fischeri, organism), and a field specifying if the data is regarded valid (ok).

Source

Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J, Hoffmann J, Ondruschka B, Filser J, Jastorff B (2004) Biological effects of imidazolium ionic liquids with varying chain lenghts in acute Vibrio fischeri and WST-1 cell viability assays. Ecotoxicology and Environmental Safety 58(3) 396-404

Examples

  rIM1xVibrio <- drfit(IM1xVibrio, logit = TRUE, chooseone = FALSE,
                       showED50 = TRUE, EDx = c(10, 20))
  print(rIM1xVibrio, digits = 4)

  rIM1xVibrio.drc <- drcfit(IM1xVibrio, logit = TRUE, chooseone = FALSE,
                            showED50 = TRUE, EDx = c(10, 20))
  print(rIM1xVibrio.drc, digits = 4)

Example output

IM13 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM14 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM15 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM16 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM17 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM18 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM19 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...

IM1-10 BF4: Fitting data...

Waiting for profiling to be done...
Waiting for profiling to be done...
    Substance ndl  n    lld   lhd  mtype logED50    2.5%   97.5%   unit   sigma
1    IM13 BF4  13 22 -5.301 4.699 probit  3.9399  3.8636  4.0160 microM 0.06303
2    IM13 BF4  13 22 -5.301 4.699  logit  3.9461  3.8708  4.0211 microM 0.06188
3    IM14 BF4  12 57 -4.301 4.699 probit  3.5442  3.5030  3.5855 microM 0.05905
4    IM14 BF4  12 57 -4.301 4.699  logit  3.5465  3.5044  3.5885 microM 0.06030
5    IM15 BF4   7 20 -0.301 4.699 probit  3.1398  3.1136  3.1662 microM 0.02695
6    IM15 BF4   7 20 -0.301 4.699  logit  3.1387  3.1118  3.1659 microM 0.02723
7    IM16 BF4  13 30 -4.301 4.699 probit  3.1804  3.1436  3.2176 microM 0.04514
8    IM16 BF4  13 30 -4.301 4.699  logit  3.1814  3.1440  3.2190 microM 0.04553
9    IM17 BF4  10 20 -1.301 4.699 probit  2.4317  2.3681  2.4951 microM 0.04773
10   IM17 BF4  10 20 -1.301 4.699  logit  2.4353  2.3672  2.5026 microM 0.05050
11   IM18 BF4  10 17 -2.301 2.699 probit  1.4015  1.3147  1.4881 microM 0.05611
12   IM18 BF4  10 17 -2.301 2.699  logit  1.4051  1.3129  1.4966 microM 0.05898
13   IM19 BF4  13 22 -5.301 2.699 probit  0.7158  0.6704  0.7592 microM 0.02956
14   IM19 BF4  13 22 -5.301 2.699  logit  0.7172  0.6689  0.7635 microM 0.03210
15 IM1-10 BF4  11 20 -6.301 2.699 probit -0.1790 -0.2569 -0.1037 microM 0.04099
16 IM1-10 BF4  11 20 -6.301 2.699  logit -0.1831 -0.2620 -0.1055 microM 0.04192
         a      b      ED50 ED50 2.5% ED50 97.5%     EDx10    EDx20
1   3.9399 0.5763 8707.8956 7305.0279  1.038e+04 1.590e+03 2850.222
2   3.9461 0.3426 8832.9407 7426.2282  1.050e+04 1.561e+03 2959.147
3   3.5442 0.6561 3501.1558 3184.3196  3.851e+03 5.051e+02  981.759
4   3.5465 0.3911 3519.5779 3194.6808  3.877e+03 4.867e+02 1010.014
5   3.1398 0.5527 1379.9037 1298.9533  1.466e+03 2.701e+02  472.823
6   3.1387 0.3347 1376.4086 1293.7152  1.465e+03 2.532e+02  472.911
7   3.1804 0.4882 1515.0421 1391.8150  1.650e+03 3.588e+02  588.292
8   3.1814 0.2957 1518.4650 1393.2665  1.656e+03 3.401e+02  590.840
9   2.4317 0.6387  270.2279  233.3814  3.127e+02 4.105e+01   78.382
10  2.4353 0.3810  272.4409  232.9287  3.182e+02 3.965e+01   80.754
11  1.4015 0.8009   25.2069   20.6383  3.077e+01 2.372e+00    5.340
12  1.4051 0.4816   25.4135   20.5545  3.138e+01 2.222e+00    5.463
13  0.7158 0.6969    5.1975    4.6814  5.744e+00 6.647e-01    1.347
14  0.7172 0.4132    5.2141    4.6652  5.801e+00 6.446e-01    1.394
15 -0.1790 0.8019    0.6622    0.5534  7.876e-01 6.212e-02    0.140
16 -0.1831 0.4816    0.6560    0.5470  7.843e-01 5.738e-02    0.141

IM13 BF4: Fitting data...


IM14 BF4: Fitting data...


IM15 BF4: Fitting data...


IM16 BF4: Fitting data...


IM17 BF4: Fitting data...


IM18 BF4: Fitting data...


IM19 BF4: Fitting data...


IM1-10 BF4: Fitting data...

    Substance ndl  n    lld   lhd  mtype logED50    2.5%   97.5%   unit   sigma
1    IM13 BF4  13 22 -5.301 4.699 probit  3.9399  3.8563  4.0100 microM 0.06303
2    IM13 BF4  13 22 -5.301 4.699  logit  3.9461  3.8637  4.0153 microM 0.06188
3    IM14 BF4  12 57 -4.301 4.699 probit  3.5442  3.5009  3.5836 microM 0.05905
4    IM14 BF4  12 57 -4.301 4.699  logit  3.5465  3.5023  3.5866 microM 0.06030
5    IM15 BF4   7 20 -0.301 4.699 probit  3.1398  3.1127  3.1654 microM 0.02695
6    IM15 BF4   7 20 -0.301 4.699  logit  3.1387  3.1109  3.1649 microM 0.02723
7    IM16 BF4  13 30 -4.301 4.699 probit  3.1804  3.1419  3.2158 microM 0.04514
8    IM16 BF4  13 30 -4.301 4.699  logit  3.1814  3.1424  3.2172 microM 0.04553
9    IM17 BF4  10 20 -1.301 4.699 probit  2.4317  2.3632  2.4909 microM 0.04773
10   IM17 BF4  10 20 -1.301 4.699  logit  2.4353  2.3618  2.4981 microM 0.05050
11   IM18 BF4  10 17 -2.301 2.699 probit  1.4015  1.3052  1.4803 microM 0.05611
12   IM18 BF4  10 17 -2.301 2.699  logit  1.4051  1.3023  1.4881 microM 0.05898
13   IM19 BF4  13 22 -5.301 2.699 probit  0.7158  0.6690  0.7580 microM 0.02956
14   IM19 BF4  13 22 -5.301 2.699  logit  0.7172  0.6672  0.7620 microM 0.03210
15 IM1-10 BF4  11 20 -6.301 2.699 probit -0.1790 -0.2628 -0.1088 microM 0.04099
16 IM1-10 BF4  11 20 -6.301 2.699  logit -0.1831 -0.2690 -0.1114 microM 0.04192
           a       b      ED50 ED50 2.5% ED50 97.5%     EDx10 EDx10 2.5%
1  8707.5571 -0.7536 8707.5571 7183.0127  1.023e+04 1.590e+03  968.72501
2  8832.8773  1.2676 8832.8773 7306.8669  1.036e+04 1.561e+03  925.39582
3  3501.1967 -0.6619 3501.1967 3168.9639  3.833e+03 5.051e+02  395.26341
4  3519.5773  1.1105 3519.5773 3179.2923  3.860e+03 4.866e+02  371.84710
5  1379.9019 -0.7858 1379.9019 1296.3162  1.463e+03 2.701e+02  233.25320
6  1376.4086  1.2976 1376.4086 1290.8397  1.462e+03 2.531e+02  215.79719
7  1515.0427 -0.8896 1515.0427 1386.3308  1.644e+03 3.588e+02  283.79434
8  1518.4644  1.4686 1518.4644 1387.9173  1.649e+03 3.401e+02  262.20564
9   270.2279 -0.6800  270.2279  230.7905  3.097e+02 4.105e+01   27.78507
10  272.4526  1.1401  272.4526  230.0588  3.148e+02 3.966e+01   25.34948
11   25.2059 -0.5423   25.2059   20.1927  3.022e+01 2.372e+00    1.29116
12   25.4145  0.9017   25.4145   20.0576  3.077e+01 2.223e+00    1.09707
13    5.1971 -0.6231    5.1971    4.6665  5.728e+00 6.646e-01    0.49235
14    5.2141  1.0511    5.2141    4.6477  5.781e+00 6.446e-01    0.46046
15    0.6622 -0.5416    0.6622    0.5460  7.783e-01 6.213e-02    0.03513
16    0.6560  0.9018    0.6560    0.5383  7.737e-01 5.738e-02    0.03163
   EDx10 97.5%    EDx20 EDx20 2.5% EDx20 97.5%
1    2.211e+03 2850.328  2.019e+03   3681.2703
2    2.196e+03 2958.988  2.092e+03   3826.1457
3    6.149e+02  981.743  8.254e+02   1138.0862
4    6.014e+02 1010.061  8.414e+02   1178.7611
5    3.070e+02  472.838  4.257e+02    520.0197
6    2.905e+02  472.906  4.239e+02    521.8955
7    4.337e+02  588.259  4.999e+02    676.6627
8    4.181e+02  590.824  4.972e+02    684.4677
9    5.431e+01   78.383  5.955e+01     97.2142
10   5.396e+01   80.763  5.975e+01    101.7713
11   3.454e+00    5.339  3.544e+00      7.1350
12   3.348e+00    5.463  3.489e+00      7.4370
13   8.369e-01    1.346  1.084e+00      1.6086
14   8.288e-01    1.394  1.106e+00      1.6832
15   8.912e-02    0.140  9.501e-02      0.1850
16   8.314e-02    0.141  9.588e-02      0.1862

drfit documentation built on May 2, 2019, 2:31 p.m.