antifoul: Dose-Response data for TBT and Zink Pyrithione in IPC-81...
In drfit: Dose-Response Data Evaluation
Description
Usage
Format
Examples
Description
This data set shows the response of the rat leukaemic cell line IPC-81 to
dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
from the "cytotox" database of the UFT Department of Bioorganic Chemistry on
February 25, 2004
Usage
1
Format
A dataframe containing 135 and 81 data points for concentrations and responses
for TBT and Zink Pyrithione, respectively. Some additional columns from the
database are also present.
Examples
1
2
3
4
5
6
7
8
9
10
11
rantifoul.ED50 <- drfit(antifoul,
linlogit = TRUE, logit = TRUE, weibull = TRUE,
chooseone = FALSE,
showED50 = TRUE, EDx = c(10))
print(rantifoul.ED50, digits = 5)
rantifoul.drc <- drcfit(antifoul,
linlogit = TRUE, logit = TRUE, weibull = TRUE,
chooseone = FALSE,
showED50 = TRUE, EDx = c(10))
print(rantifoul.drc, digits = 5)
Example output
TBT: Fitting data...
Waiting for profiling to be done...
Waiting for profiling to be done...
Waiting for profiling to be done...
Zn Pyrithion: Fitting data...
Waiting for profiling to be done...
Waiting for profiling to be done...
Waiting for profiling to be done...
Substance ndl n lld lhd mtype logED50 2.5% 97.5%
1 TBT 38 135 -2.7093 2.3979 linlogit -0.15809 -0.26021 -0.050475
2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.26504 -0.056498
3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.26116 -0.052591
4 TBT 38 135 -2.7093 2.3979 weibull -0.11507 NA NA
5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41329 -0.52932 -0.299799
6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.50783 -0.291563
7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.51049 -0.293501
8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.38795 NA NA
unit sigma a b c ED50 ED50 2.5% ED50 97.5%
1 microM 0.19264 -0.15809 1.04065 -0.024165 0.69487 0.54927 0.89028
2 microM 0.19286 -0.16436 0.67637 NA 0.68493 0.54320 0.87801
3 microM 0.19199 -0.16012 0.41358 NA 0.69164 0.54808 0.88595
4 microM 0.18810 0.63743 1.28891 NA 0.76724 NA NA
5 microM 0.22878 -0.41329 1.74249 0.610811 0.38611 0.29558 0.50142
6 microM 0.22866 -0.39792 0.41696 NA 0.40002 0.31058 0.51102
7 microM 0.22802 -0.40035 0.25395 NA 0.39779 0.30868 0.50874
8 microM 0.23008 0.47647 2.51561 NA 0.40931 NA NA
EDx10
1 0.085214
2 0.093077
3 0.085340
4 0.053392
5 0.120232
6 0.116872
7 0.110068
8 0.121166
TBT: Fitting data...
Zn Pyrithion: Fitting data...
Substance ndl n lld lhd mtype logED50 2.5% 97.5%
1 TBT 38 135 -2.7093 2.3979 linlogit NA NA NA
2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.28178 -0.072022
3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.27782 -0.067603
4 TBT 38 135 -2.7093 2.3979 weibull -0.13012 -0.23786 -0.043860
5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41330 -0.54457 -0.312631
6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.52005 -0.302705
7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.52324 -0.304676
8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.37351 -0.49792 -0.276917
unit sigma a b c ED50 ED50 2.5% ED50 97.5%
1 microM 0.19264 0.71806 1.04061 -0.024169 NA NA NA
2 microM 0.19286 0.68492 -0.64209 NA 0.68492 0.52267 0.84718
3 microM 0.19199 0.69165 1.05007 NA 0.69165 0.52744 0.85585
4 microM 0.18900 -0.13012 0.79816 NA 0.74111 0.57828 0.90394
5 microM 0.22878 0.30926 1.74257 0.611358 0.38610 0.28538 0.48682
6 microM 0.22866 0.40002 -1.04159 NA 0.40002 0.30196 0.49808
7 microM 0.22802 0.39779 1.71015 NA 0.39779 0.29975 0.49582
8 microM 0.23077 -0.37351 1.19152 NA 0.42315 0.31775 0.52855
EDx10 EDx10 2.5% EDx10 97.5%
1 NA NA NA
2 0.093074 0.040308 0.14584
3 0.085338 0.035963 0.13471
4 0.069958 0.026197 0.11372
5 0.120238 0.043513 0.19696
6 0.116878 0.048151 0.18561
7 0.110068 0.043085 0.17705
8 0.087066 0.017958 0.15617
drfit documentation built on May 2, 2019, 2:31 p.m.
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Description Usage Format Examples
Description
This data set shows the response of the rat leukaemic cell line IPC-81 to dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved from the "cytotox" database of the UFT Department of Bioorganic Chemistry on February 25, 2004
Usage
1 |
Format
A dataframe containing 135 and 81 data points for concentrations and responses for TBT and Zink Pyrithione, respectively. Some additional columns from the database are also present.
Examples
1 2 3 4 5 6 7 8 9 10 11 | rantifoul.ED50 <- drfit(antifoul,
linlogit = TRUE, logit = TRUE, weibull = TRUE,
chooseone = FALSE,
showED50 = TRUE, EDx = c(10))
print(rantifoul.ED50, digits = 5)
rantifoul.drc <- drcfit(antifoul,
linlogit = TRUE, logit = TRUE, weibull = TRUE,
chooseone = FALSE,
showED50 = TRUE, EDx = c(10))
print(rantifoul.drc, digits = 5)
|
Example output
TBT: Fitting data...
Waiting for profiling to be done...
Waiting for profiling to be done...
Waiting for profiling to be done...
Zn Pyrithion: Fitting data...
Waiting for profiling to be done...
Waiting for profiling to be done...
Waiting for profiling to be done...
Substance ndl n lld lhd mtype logED50 2.5% 97.5%
1 TBT 38 135 -2.7093 2.3979 linlogit -0.15809 -0.26021 -0.050475
2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.26504 -0.056498
3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.26116 -0.052591
4 TBT 38 135 -2.7093 2.3979 weibull -0.11507 NA NA
5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41329 -0.52932 -0.299799
6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.50783 -0.291563
7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.51049 -0.293501
8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.38795 NA NA
unit sigma a b c ED50 ED50 2.5% ED50 97.5%
1 microM 0.19264 -0.15809 1.04065 -0.024165 0.69487 0.54927 0.89028
2 microM 0.19286 -0.16436 0.67637 NA 0.68493 0.54320 0.87801
3 microM 0.19199 -0.16012 0.41358 NA 0.69164 0.54808 0.88595
4 microM 0.18810 0.63743 1.28891 NA 0.76724 NA NA
5 microM 0.22878 -0.41329 1.74249 0.610811 0.38611 0.29558 0.50142
6 microM 0.22866 -0.39792 0.41696 NA 0.40002 0.31058 0.51102
7 microM 0.22802 -0.40035 0.25395 NA 0.39779 0.30868 0.50874
8 microM 0.23008 0.47647 2.51561 NA 0.40931 NA NA
EDx10
1 0.085214
2 0.093077
3 0.085340
4 0.053392
5 0.120232
6 0.116872
7 0.110068
8 0.121166
TBT: Fitting data...
Zn Pyrithion: Fitting data...
Substance ndl n lld lhd mtype logED50 2.5% 97.5%
1 TBT 38 135 -2.7093 2.3979 linlogit NA NA NA
2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.28178 -0.072022
3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.27782 -0.067603
4 TBT 38 135 -2.7093 2.3979 weibull -0.13012 -0.23786 -0.043860
5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41330 -0.54457 -0.312631
6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.52005 -0.302705
7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.52324 -0.304676
8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.37351 -0.49792 -0.276917
unit sigma a b c ED50 ED50 2.5% ED50 97.5%
1 microM 0.19264 0.71806 1.04061 -0.024169 NA NA NA
2 microM 0.19286 0.68492 -0.64209 NA 0.68492 0.52267 0.84718
3 microM 0.19199 0.69165 1.05007 NA 0.69165 0.52744 0.85585
4 microM 0.18900 -0.13012 0.79816 NA 0.74111 0.57828 0.90394
5 microM 0.22878 0.30926 1.74257 0.611358 0.38610 0.28538 0.48682
6 microM 0.22866 0.40002 -1.04159 NA 0.40002 0.30196 0.49808
7 microM 0.22802 0.39779 1.71015 NA 0.39779 0.29975 0.49582
8 microM 0.23077 -0.37351 1.19152 NA 0.42315 0.31775 0.52855
EDx10 EDx10 2.5% EDx10 97.5%
1 NA NA NA
2 0.093074 0.040308 0.14584
3 0.085338 0.035963 0.13471
4 0.069958 0.026197 0.11372
5 0.120238 0.043513 0.19696
6 0.116878 0.048151 0.18561
7 0.110068 0.043085 0.17705
8 0.087066 0.017958 0.15617
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