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An implementation of a variety of escalation with overdose control designs introduced by Babb, Rogatko and Zacks (1998) <doi:10.1002/(SICI)1097-0258(19980530)17:10%3C1103::AID-SIM793%3E3.0.CO;2-9>. It calculates the next dose as a clinical trial proceeds and performs simulations to obtain operating characteristics.
Package details |
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| Author | Marcio A. Diniz <marcio.diniz@cshs.org> |
| Maintainer | Marcio A. Diniz <marcio.diniz@cshs.org> |
| License | GPL (>= 2) |
| Version | 0.3.0 |
| URL | https://github.com/dnzmarcio/ewoc/ |
| Package repository | View on CRAN |
| Installation |
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