Plot the DLT curve based on the EWOC proportional hazards model
1 2 3 4 5 6 7 8 9 10 11 | dlt_curve_d1ph(
mtd,
rho,
theta,
min_dose,
max_dose,
shape,
tau,
distribution = "exponential",
dose_set = NULL
)
|
mtd |
a numerical value indicating the true value of the parameter mtd. |
rho |
a numerical value indicating the true value of the parameter rho. |
theta |
a numerical value defining the proportion of expected patients to experience a medically unacceptable, dose-limiting toxicity (DLT) if administered the MTD. |
min_dose |
a numerical value defining the lower bound of the support of the MTD. |
max_dose |
a numerical value defining the upper bound of the support of the MTD. |
shape |
a numerical value indicating the true value of the parameter shape. It is only necessary if 'distribution' = "weibull". |
tau |
a numerical value defining the period of time for a possible toxicity be observed. |
distribution |
a character establishing the distribution for the time of events. It can be defined as 'exponential' or 'weibull'. |
dose_set |
a numerical vector of doses that probability of DLT will be calculated. |
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