calculate_log2_fold_change: Calculate log2 fold change with consistent pseudocount...

In ggpicrust2: Make 'PICRUSt2' Output Analysis and Visualization Easier

Calculate log2 fold change with consistent pseudocount handling

Description

Calculates log2 fold change between two groups with proper handling of zero values using a data-driven pseudocount approach.

Usage

calculate_log2_fold_change(
  mean1,
  mean2,
  pseudocount = NULL,
  reference_values = NULL
)

Arguments

mean1	Numeric. Mean abundance of group 1 (reference/control)
mean2	Numeric. Mean abundance of group 2 (comparison/treatment)
pseudocount	Optional numeric. If NULL, calculated from reference_values
reference_values	Optional numeric vector for calculating pseudocount

Details

The fold change direction is group2/group1, so: - Positive values indicate higher abundance in group2 - Negative values indicate higher abundance in group1

Value

log2(mean2/mean1) with pseudocount protection

ggpicrust2 documentation built on April 10, 2026, 5:06 p.m.