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hlaR: Tools for HLA Data
A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.
Getting started
Browse package contents
Package details |
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| Author | Joan Zhang [aut, cre], Aileen Johnson [aut], Christian P Larsen [cph, aut] |
| Maintainer | Joan Zhang <joan.zhang@emory.edu> |
| License | MIT + file LICENSE |
| Version | 1.0.0 |
| URL | https://pubmed.ncbi.nlm.nih.gov/35101308/ https://emory-larsenlab.shinyapps.io/hlar_shiny/ |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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