hlaR: Tools for HLA Data

A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

Package details

AuthorJoan Zhang [aut, cre], Aileen Johnson [aut], Christian P Larsen [cph, aut]
MaintainerJoan Zhang <joan.zhang@emory.edu>
LicenseMIT + file LICENSE
URL https://pubmed.ncbi.nlm.nih.gov/35101308/ https://emory-larsenlab.shinyapps.io/hlar_shiny/
Package repositoryView on CRAN
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hlaR documentation built on Feb. 16, 2023, 7:04 p.m.