CalAlleleMismFreq: Evaluate the frequency of specific allele mismatches

In hlaR: Tools for HLA Data

Evaluate the frequency of specific allele mismatches

Description

This function evaluates allele level mismatch between donor and recipient and then presents the most commonly mismatched alleles. This function is most effectively used to study the most common mismatches within a transplant population.

Usage

CalAlleleMismFreq(dat_in, nms_don = c(), nms_rcpt = c())

Arguments

dat_in	A data frame of clean HLA typing data.
nms_don	A vector of column names of donor's alleles, must be length of 2.
nms_rcpt	A vector of column names of recipient's alleles, must be length of 2.

Value

A data frame of donor's mismatched alleles with frequency > 1. No mismatch is calculated if input alleles are NA.

Examples

dat <- read.csv(system.file("extdata/example", "HLA_MisMatch_test.csv", package = "hlaR"))
don <- c("donor.a1", "donor.a2")
rcpt <- c("recipient.a1", "recipient.a2")
re <- CalAlleleMismFreq(dat_in = dat, nms_don = don, nms_rcpt = rcpt)

hlaR documentation built on Feb. 16, 2023, 7:04 p.m.