invitroTKdata: In Vitro Toxicokinetic Data Processed with the 'invitroTKstats' Pipeline

A collection of datasets containing a variety of in vitro toxicokinetic measurements including -- but not limited to -- chemical fraction unbound in the presence of plasma (f_up), intrinsic hepatic clearance (Clint, uL/min/million hepatocytes), and membrane permeability for oral absorption (Caco2). The datasets provided by the package were processed and analyzed with the companion 'invitroTKstats' package.

Getting started

Package details

AuthorSarah E. Davidson-Fritz [aut, cre] (ORCID: <https://orcid.org/0000-0002-2891-9380>), John Wambaugh [aut] (ORCID: <https://orcid.org/0000-0002-4024-534X>), Lindsay Knupp [ctb], Barbara A. Wetmore [ctb] (ORCID: <https://orcid.org/0000-0002-6878-5348>), Anna Kreutz [ctb] (ORCID: <https://orcid.org/0000-0002-7787-0683>), Marci Smeltz [ctb] (ORCID: <https://orcid.org/0000-0001-9723-8696>), David Crizer [ctb], U.S. Federal Government [cph] (Copyright holder of this package)
MaintainerSarah E. Davidson-Fritz <davidsonfritz.sarah@epa.gov>
LicenseMIT + file LICENSE
Version0.0.1
URL https://github.com/USEPA/invitroTKdata
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("invitroTKdata")

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invitroTKdata documentation built on Aug. 21, 2025, 5:56 p.m.