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A collection of datasets containing a variety of in vitro toxicokinetic measurements including -- but not limited to -- chemical fraction unbound in the presence of plasma (f_up), intrinsic hepatic clearance (Clint, uL/min/million hepatocytes), and membrane permeability for oral absorption (Caco2). The datasets provided by the package were processed and analyzed with the companion 'invitroTKstats' package.
Package details |
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Author | Sarah E. Davidson-Fritz [aut, cre] (ORCID: <https://orcid.org/0000-0002-2891-9380>), John Wambaugh [aut] (ORCID: <https://orcid.org/0000-0002-4024-534X>), Lindsay Knupp [ctb], Barbara A. Wetmore [ctb] (ORCID: <https://orcid.org/0000-0002-6878-5348>), Anna Kreutz [ctb] (ORCID: <https://orcid.org/0000-0002-7787-0683>), Marci Smeltz [ctb] (ORCID: <https://orcid.org/0000-0001-9723-8696>), David Crizer [ctb], U.S. Federal Government [cph] (Copyright holder of this package) |
Maintainer | Sarah E. Davidson-Fritz <davidsonfritz.sarah@epa.gov> |
License | MIT + file LICENSE |
Version | 0.0.1 |
URL | https://github.com/USEPA/invitroTKdata |
Package repository | View on CRAN |
Installation |
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