kreutz2023.uc.L4: \insertCitekreutz2023category;textualinvitroTKdata...

In invitroTKdata: In Vitro Toxicokinetic Data Processed with the 'invitroTKstats' Pipeline

\insertCitekreutz2023category;textualinvitroTKdata Ultracentrifugation Level-4 Data Set

Description

Bayesian estimates of plasma protein binding measured by ultracentrifugation (UC) for per- and poly-fluorinated alkyl substance (PFAS) samples from experiments led by Dr.s Anna Kreutz and Barbara Wetmore.

Usage

kreutz2023.uc.L4

Format

A level-4 data.frame with 52 rows and 13 variables:

Compound.Name

Compound name

DTXSID

DSSTox Substance Identifier (CompTox Chemicals Dashboard)

Lab.Compound.Name

Compound as described in the laboratory

Fstable.Med

Posterior median chemical stability fraction

Fstable.Low

Posterior 2.5th quantile chemical stability fraction (lower credible interval bound)

Fstable.High

Posterior 97.5th quantile chemical stability fraction (upper credible interval bound)

Fup.Med

Posterior median fraction unbound in plasma

Fup.Low

Posterior 2.5th quantile of fraction unbound in plasma (lower credible interval bound)

Fup.High

Posterior 97.5th quantile of fraction unbound in plasma (upper credible interval bound)

Fup.point

Point estimate of fraction unbound in plasma

Unstable

Qualitative determination of chemical stability. "Y" indicates observed chemical stability.

Uncertain

Qualitative determination of uncertainty about chemical stability. "Y" indicates uncertainty in observed chemical stability.

CV

Coefficient of variance

References

\insertRef

howard2010plasmainvitroTKdata

\insertRef

kreutz2023categoryinvitroTKdata

invitroTKdata documentation built on Aug. 21, 2025, 5:56 p.m.