wambaugh2019.red.L4: \insertCitewambaugh2019assessing;textualinvitroTKdata Rapid...

In invitroTKdata: In Vitro Toxicokinetic Data Processed with the 'invitroTKstats' Pipeline

\insertCitewambaugh2019assessing;textualinvitroTKdata Rapid Equilibrium Dialysis Level-4 Data Set

Description

Bayesian estimate of plasma protein binding using the rapid equilibrium dialysis (RED) assay method \insertCitewaters2008validationinvitroTKdata.

Usage

wambaugh2019.red.L4

Format

A data.frame 301 rows and 7 variables:

Compound.Name

Compound name

Lab.Compound.Name

Compound as described in the laboratory

DTXSID

DSSTox Substance Identifier (CompTox Chemical Dashboard)

Fup.point

Point estimate of fraction unbound in plasma

Fup.Med

Posterior median fraction unbound in plasma

Fup.Low

Posterior 2.5th quantile of fraction unbound in plasma (lower credible interval bound)

Fup.High

Posterior 97.5th quantile of fraction unbound in plasma (upper credible interval bound)

Source

Wambaugh et al. (2019)

References

\insertRef

waters2008validationinvitroTKdata

\insertRef

wambaugh2019assessinginvitroTKdata

invitroTKdata documentation built on Aug. 21, 2025, 5:56 p.m.