Method for the calculation of copy numbers and calling of copy number alterations. The algorithm uses coverage data from amplicon sequencing of a sample cohort as input. The method includes significance assessment, correction for multiple testing and does not depend on normal DNA controls.
|Date of publication||2015-08-26 14:53:52|
|Maintainer||Jan Budczies <firstname.lastname@example.org>|
calculate.CN: Calculation of copy numbers
call.amplicons: Amplicon-wise call of copy number alterations
call.genes: Gene-wise calling of copy number alterations
coverage: Coverage data of 154 amplicons in 184 breast carcinomas
ioncopy-package: Calling copy number alterations in amplicon sequencing data