Calling copy number alterations in amplicon sequencing data


Method for the calculation of copy numbers and calling of copy number alterations. The algorithm uses coverage data from amplicon sequencing of a sample cohort as input. The method includes significance assessment, correction for multiple testing and does not depend on normal DNA controls.


Package: ioncopy
Type: Package
Version: 1.0
Date: 2015-08-25
License: GPL-3


Jan Budczies <>


Jan Budczies, Nicole Pfarr, Albrecht Stenzinger, Denise Treue, Volker Endris, Fakher Ismaeel, Nikola Bangemann, Jens-Uwe Blohmer, Manfred Dietel, Sibylle Loibl, Wilko Weichert, Carsten Denkert: Ioncopy: A novel method for calling copy number alterations in amplicon sequencing data including significance assessment. Submitted.

comments powered by Disqus