Description Usage Arguments Value Author(s) See Also
Returns the minimum value of r2 in r2.vec that keeps the number of constraint matrix columns less than maxcol.
1 | r2.cut.fn(block.obj, block.cood, Xa, Y, maxcol, r2.cut.min, r2.cut.max, r2.vec.length)
|
block.obj |
An object of class gwaa.data from GenABEL. |
block.cood |
A vector of length p+1, where p is the number of SNPs. block.cood is an indicator vector that indicates block boundaries at all p+1 SNP bounded intervals. Use find.bounds to create this vector. |
Xa |
If block.obj is NA then a genotype matrix must be provided. Xa is a matrix of genotype values codes as 0, 1 or 2 for homozygous major, heterozygous, or homozygous minor, respectively. |
Y |
If block.obj is NA then a phenotype vector Y must be provided. Y is a vector of diagnoses, where 0 is non-diseased and 1 is diseased. |
maxcol |
The maximum number of columns allowed in the constraint matrix. Default is 5,000. |
r2.cut.min |
The lower bound of the r2.cut interval |
r2.cut.max |
The upper bound of the r2.cut interval |
r2.vec.length |
The number of r2.cut values uniformly spaced in r2.cut interval |
The function r2.cut.fn returns the minimum value of r2.cut that satsisfies, ncol(A) < maxcol, where A is the constraint matrix
Samuel G. Younkin
ld_lasso
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