dat.quan2000: Studies on Pharmacotherapy for Hypertension

In metadat: Meta-Analysis Datasets

Studies on Pharmacotherapy for Hypertension

Description

Results from 11 studies evaluating pharmacotherapy in patients with hypertension.

Usage

dat.quan2000

Format

The data frame contains the following columns:

study	character	study label
Ee	integer	fatal cerebrovascular events (pharmacotherapy)
Ne	integer	number of patients (pharmacotherapy)
Ec	integer	fatal cerebrovascular events (control)
Nc	integer	number of patients (control)

Details

Quan et al. (2000) conducted a Cochrane Review to evaluate whether the benefit of treating hypertension in women differed between younger and older women, as well as between white and African American women. In the systematic review, the Peto method was used for pooling. The primary outcome was the occurrence of fatal cerebrovascular events, a rare event in hypertension. The dataset contains the subgroup of women older than 55 years.

This data set is used as an example in Schwarzer et al. (2015).

Concepts

medicine, cardiology, Peto's method

Author(s)

Guido Schwarzer, [e-mail], https://github.com/guido-s/

Source

Quan, A. P., Kerlikowske, K., Gueyffier, F., Boissel, J.-P., & INDANA Investigators (2010). Pharmacotherapy for hypertension in women of different races. Cochrane Database of Systematic Reviews, 2, CD002146. ⁠https://doi.org/10.1002/14651858.cd002146⁠

References

Schwarzer, G., Carpenter, J. R., & Rücker, G. (2015). Meta-analysis with R. Cham, Switzerland: Springer.

Examples

### Show first five studies
head(dat.quan2000, 5)

## Not run: 
### Load meta package
suppressPackageStartupMessages(library(meta))

### Use RevMan 5 settings
oldset <- settings.meta("RevMan5")

### Conduct meta-analyis with Peto method
m <- metabin(Ee, Ne, Ec, Nc, sm = "OR", method = "Peto",
  data = dat.quan2000, studlab = study, random = FALSE)
m

### Use previous settings
settings.meta(oldset)

## End(Not run)

metadat documentation built on April 29, 2026, 5:10 p.m.