mrgsolve: Simulate from ODE-Based Population PK/PD and Systems Pharmacology Models
Version 0.8.12

Facilitates simulation from hierarchical, ordinary differential equation (ODE) based models typically employed in drug development. A model specification file is created consisting of R and C++ code that is parsed, compiled, and dynamically loaded into the R session. Input data are passed in and simulated data are returned as R objects. A dosing event engine allows interventions (bolus and infusion) to be managed separately from the model code. Differential equations are solved with the 'DLSODA' routine in 'ODEPACK' ().

Getting started

Package details

AuthorKyle T Baron [aut, cre], Alan C Hindmarsh [ctb], Linda R Petzold [ctb], Bill Gillespie [ctb], Charles Margossian [ctb], Devin Pastoor [ctb], Metrum Research Group LLC [cph]
Date of publication2018-04-27 20:45:52 UTC
MaintainerKyle T Baron <[email protected]>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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mrgsolve documentation built on April 28, 2018, 1:04 a.m.