ev_rx: Create intervention objects from Rx input

In mrgsolve: Simulate from ODE-Based Models

Create intervention objects from Rx input

Description

See details below for Rx specification. Actual parsing is done by parse_rx(); this function can be used to debug Rx inputs.

Usage

ev_rx(x, y, ...)

## S4 method for signature 'mrgmod,character'
ev_rx(x, y, ...)

## S4 method for signature 'character,missing'
ev_rx(x, df = FALSE, ...)

parse_rx(x)

Arguments

x	a model object or character Rx input.
y	character Rx input; see details.
...	not used at this time.
df	if TRUE then a data frame is returned.

Value

The method dispatched on model object (mrgmod) returns another model object. The character method returns an event object. The parse_rx function return a list named with arguments for the event object constructor ev().

Rx specification

• The dose is found at the start of the string by sequential digits; this may be integer, decimal, or specified in scientific notation

• Use ⁠in⁠ to identify the dosing compartment number; must be integer

• Use q to identify the dosing interval; must be integer or decimal number (but not scientific notation)

• Use over to indicate an infusion and its duration; integer or decimal number

• Use x to indicate total number of doses; must be integer

• Use then or ⁠,⁠ to separate dosing periods

• Use after to insert a lag in the start of a period; integer or decimal number (but not scientific notation)

• Use & to implement multiple doses at the same time

Examples

# example("ev_rx")

ev_rx("100")

ev_rx("100 in 2")

ev_rx("100 q12 x 3")

ev_rx("100 over 2")

ev_rx("100 q 24 x 3 then 50 q12 x 2")

ev_rx("100 then 50 q 24 after 12")

ev_rx("100.2E-2 q4")

ev_rx("100 over 2.23")

ev_rx("100 q 12 x 3")

ev_rx("100 in 1 & 200 in 2") 

parse_rx("100 mg q 24 then 200 mg q12")

mrgsolve documentation built on May 29, 2024, 5:37 a.m.