Description Usage Arguments Details Value Author(s) References See Also Examples
This function computes the TAI for a row permutated PhyloExpressionSet or DivergenceExpressionSet.
One can specify the number of permutations which corresponds to the number of TAI
or TDI
profiles
that are being returned as data matrix. The function then returns a TAI
or TDI
matrix holding
the TAI
or TDI
profiles of the permutated PhyloExpressionSets or DivergenceExpressionSets. This procedure
can be used for building test statistics based on the TAI
or TDI
profiles.
1 | bootMatrix(ExpressionSet, permutations = 1000)
|
ExpressionSet |
a standard PhyloExpressionSet or DivergenceExpressionSet object. |
permutations |
a numeric value specifying the number of permutations to be performed. |
The sampled TAI
or TDI
matrix samples the phylostratum or divergence-stratum vector of
a given PhyloExpressionSet or DivergenceExpressionSet and computes the corresponding TAI
or TDI
profiles
of the randomly assigned phylostrata or divergence-strata. This sampling is then performed N times, yielding N randomly sampled TAI
or TDI
profiles.
This random TAI
or TDI
profile matrix can then be used to perform statistical tests
(such as the FlatLineTest
, ReductiveHourglassTest
, or EarlyConservationTest
) based on the significance of TAI
or TDI
patterns.
a numeric matrix representing N randomly permuted TAI
or TDI
profiles.
Hajk-Georg Drost
Quint M et al. (2012). A transcriptomic hourglass in plant embryogenesis. Nature (490): 98-101.
Drost HG et al. (2015) Mol Biol Evol. 32 (5): 1221-1231 doi:10.1093/molbev/msv012
FlatLineTest
, ReductiveHourglassTest
, EarlyConservationTest
1 2 3 4 5 6 7 8 9 | # read standard phylotranscriptomics data
data(PhyloExpressionSetExample)
data(DivergenceExpressionSetExample)
# example PhyloExpressionSet using 100 permutations
randomTAI.Matrix <- bootMatrix(PhyloExpressionSetExample, permutations = 100)
# example DivergenceExpressionSet using 100 permutations
randomTDI.Matrix <- bootMatrix(DivergenceExpressionSetExample, permutations = 100)
|
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