nlmixr2est: Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Getting started

Package details

AuthorMatthew Fidler [aut, cre] (<>), Yuan Xiong [aut], Rik Schoemaker [aut] (<>), Justin Wilkins [aut] (<>), Wenping Wang [aut], Robert Leary [ctb], Mason McComb [ctb] (<>), Vipul Mann [aut], Mirjam Trame [ctb], Mahmoud Abdelwahab [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Katharine Mullen [cph], Ben Goodrich [ctb]
MaintainerMatthew Fidler <>
LicenseGPL (>= 3)
Package repositoryView on CRAN
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nlmixr2est documentation built on Oct. 8, 2023, 9:06 a.m.