approx_theta_post | R Documentation |
Laplace approximation of the posterior of allelic imbalance theta
approx_theta_post(
pAD,
DP,
p_s,
lower = 0.001,
upper = 0.499,
start = 0.25,
gamma = 20
)
pAD |
numeric vector Variant allele depth |
DP |
numeric vector Total allele depth |
p_s |
numeric vector Variant allele frequency |
lower |
numeric Lower bound of theta |
upper |
numeric Upper bound of theta |
start |
numeric Starting value of theta |
gamma |
numeric Gamma parameter of the beta-binomial distribution |
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