approx_theta_post: Laplace approximation of the posterior of allelic imbalance...
In numbat: Haplotype-Aware CNV Analysis from scRNA-Seq

approx_theta_post

R Documentation

Laplace approximation of the posterior of allelic imbalance theta

Laplace approximation of the posterior of allelic imbalance theta

approx_theta_post(
  pAD,
  DP,
  p_s,
  lower = 0.001,
  upper = 0.499,
  start = 0.25,
  gamma = 20
)

`pAD`	numeric vector Variant allele depth
`DP`	numeric vector Total allele depth
`p_s`	numeric vector Variant allele frequency
`lower`	numeric Lower bound of theta
`upper`	numeric Upper bound of theta
`start`	numeric Starting value of theta
`gamma`	numeric Gamma parameter of the beta-binomial distribution