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#' Budget and/or sample size, power, MDES calculation for
#' single-level experiments detecting main effects
#'
#' @description This function can calculate required budget for desired power,
#' power or minimum detectable effect size (MDES) under fixed budget
#' for single-level experiments.
#' It also can perform conventional power analyses
#' (e.g., required sample size, power, and MDES calculation).
#'
#' @inheritParams power.4
#' @param expr Returned object from function \code{\link{od.1}}; default value is NULL;
#' if \code{expr} is specified, parameter values of \code{r12},
#' \code{c1}, \code{c1t}, and \code{p}
#' used or solved in function \code{\link{od.1}} will
#' be passed to the current function;
#' only the value of \code{p} that specified or solved in
#' function \code{\link{od.1}} can be overwritten
#' if \code{constraint} is specified.
#' @param constraint Specify the constrained value of
#' \code{p} in list format to overwrite that
#' from \code{expr}; default value is NULL.
#' @param r12 The proportion of outcome variance explained by covariates.
#' @param c1 The cost of sampling one unit in control condition.
#' @param c1t The cost of sampling one unit in treatment condition.
#' @param n The total sample size.
#' @param p The proportion of individuals to be assigned to treatment.
#' @param q The number of covariates.
#' @param nlim The range for searching the root of sample size (\code{n}) numerically,
#' default value is c(4, 10e10).
#' @param mlim The range for searching the root of budget (\code{m}) numerically,
#' default value is the costs sampling \code{nlim} units across treatment conditions
#' or c(4 * ncost, 10e10 * ncost) with ncost = ((1 - p) * c1 + p * c1t).
#' @param rounded Logical; round \code{p} that is from functions \code{od.1}
#' to two decimal places if TRUE,
#' otherwise no rounding; default value is TRUE.
#'
#' @return Required budget (or required sample size), statistical power, or MDES
#' depending on the specification of parameters.
#' The function also returns the function name, design type,
#' and parameters used in the calculation.
#'
#' @export power.1
#'
#' @examples
#' # Unconstrained optimal design
#' myod1 <- od.1(r12 = 0.5, c1 = 1, c1t = 5, varlim = c(0, 0.2))
#' myod1$out # p = 0.31
#'
#' # ------- Power analyses by default considering costs and budget -------
#' # Required budget and sample size
#' mym.1 <- power.1(expr = myod1, d = 0.2, q = 1, power = 0.8)
#' mym.1$out # m = 1032 n = 461
#' # mym.1$par # parameters and their values used for the function
#' # Or, equivalently, specify every argument in the function
#' mym.1 <- power.1(d = 0.2, power = 0.8, c1 = 1, c1t = 5,
#' r12 = 0.5, p = 0.31, q = 1)
#' # Required budget and sample size with constrained p
#' mym.2 <- power.1(expr = myod1, d = 0.2, q = 1, power = 0.8,
#' constraint = list(p = 0.5))
#' mym.2$out # m = 1183, n = 394
#'
#' # Power calculation
#' mypower <- power.1(expr = myod1, q = 1, d = 0.2, m = 1032)
#' mypower$out # power = 0.80
#' # Power calculation under constrained p (p = 0.5)
#' mypower.1 <- power.1(expr = myod1, q = 1, d = 0.2, m = 1032,
#' constraint = list(p = 0.5))
#' mypower.1$out # power = 0.74
#'
#' # MDES calculation
#' mymdes <- power.1(expr = myod1, q = 1, power = 0.80, m = 1032)
#' mymdes$out # d = 0.20
#'
#'
#' # ------- Conventional power analyses with cost.model = FALSE-------
#' # Required sample size n
#' myn <- power.1(cost.model = FALSE, expr = myod1, d = 0.2, q = 1, power = 0.8)
#' myn$out # n = 461
#' # myn$par # parameters and their values used for the function
#' # Or, equivalently, specify every argument in the function
#' myn <- power.1(cost.model = FALSE, d = 0.2, power = 0.8,
#' r12 = 0.5, p = 0.31, q = 1)
#'
#' # Power calculation
#' mypower1 <- power.1(cost.model = FALSE, expr = myod1, n = 461, d = 0.2, q = 1)
#' mypower1$out # power = 0.80
#'
#' # MDES calculation
#' mymdes1 <- power.1(cost.model = FALSE, expr = myod1, n = 461, power = 0.8, q = 1)
#' mymdes1$out # d = 0.20
#'
power.1 <- function(cost.model = TRUE, expr = NULL, constraint = NULL,
sig.level = 0.05, two.tailed = TRUE,
d = NULL, power = NULL, m = NULL,
n = NULL, p = NULL,
r12 = NULL, q = NULL,
c1 = NULL, c1t = NULL,
dlim = NULL, powerlim = NULL, nlim = NULL, mlim = NULL,
rounded = TRUE) {
funName <- "power.1"
designType <- "individual RCTs"
if (cost.model == TRUE) {
if (sum(sapply(list(m, d, power), is.null)) != 1)
stop("exactly one of 'm', 'd', and 'power' must be NULL
when cost.model is TRUE")
if (!is.null(n))
stop("'n' must be NULL when cost.model is TRUE")
} else {
if (sum(sapply(list(n, d, power), is.null)) != 1)
stop("exactly one of 'n', 'd', and 'power' must be NULL
when cost.model is FALSE")
if (!is.null(m))
stop("'m' must be NULL when cost.model is FALSE")
}
if (!is.null(expr)) {
if (expr$funName != "od.1") {
stop("'expr' can only be NULL or
the return from the function of 'od.1'")
} else {
if (sum(sapply(list(r12, c1, c1t, p),
function(x) {!is.null(x)})) >= 1)
stop("parameters of 'r12', 'c1', 'c1t', 'p'
have been specified in expr of 'od.1'")
r12 <- expr$par$r12
c1 <- expr$par$c1
c1t <- expr$par$c1t
if (rounded == TRUE) {
p <- round(expr$out$p, 2)
} else {
p <- expr$out$p
}
}
} else {
if (!is.null(constraint))
stop("'constraint' must be NULL when 'expr' is NULL")
}
NumberCheck <- function(x) {!is.null(x) && !is.numeric(x)}
if (!is.null(constraint) && !is.list(constraint))
stop("'constraint' must be in list format
(e.g., constraint = list(p = 0.5))")
if (length(constraint) > 1)
stop("'constraint' must be limited to 'p'")
if (!is.null(constraint$p)) {
if(NumberCheck(constraint$p) ||
any (0 >= constraint$p | constraint$p >= 1))
stop("constrained 'p' must be numeric in (0, 1)")
p <- constraint$p
}
if (sum(sapply(list(p, power, r12, sig.level), function(x) {
NumberCheck(x) || any(0 > x | x > 1)
})) >= 1) stop("'p', 'power', 'r12', and 'sig.level'
must be numeric in [0, 1]")
if (cost.model == TRUE){
if (sum(sapply(list(c1, c1t), function(x) {
NumberCheck(x) || x < 0})) >= 1)
stop("'c1', 'c1t' must be numeric in [0, Inf)")
if (NumberCheck(m))
stop("'m' must be numeric in [0, Inf)")
}
if (NumberCheck(q) | q < 0)
stop("'q' must be numeric in [0, 10e3]")
if (NumberCheck(d) || any(0 > d | d > 5))
stop("'d' must be numeric in [0, 5],
please transfer negative effect size to positive one if needed")
if (r12 > 0 && q == 0)
stop("'q' must be q >= 1 when r12 != 0")
par <- list(cost.model = cost.model,
sig.level = sig.level,
two.tailed = two.tailed,
d = d, r12 = r12,
c1 = c1, c1t = c1t,
n = n, p = p,
q = q, m = m, power = power)
tside <- ifelse(two.tailed == TRUE, 2, 1)
if (cost.model == TRUE) {
if (two.tailed == TRUE) {
pwr.expr <- quote({
n <- m / ((1 - p) * c1 + p * c1t);
lambda <- d * sqrt(p * (1 - p) * n) /
sqrt(1 - r12);
1 - pt(qt(1 - sig.level / tside, df = n - q - 2) ,
df = n - q - 2, lambda) +
pt(qt(sig.level / tside, df = n - q - 2),
df = n - q - 2, lambda)
})
} else {
pwr.expr <- quote({
n <- m / ((1 - p) * c1 + p * c1t);
lambda <- d * sqrt(p * (1 - p) * n) /
sqrt(1 - r12);
1 - pt(qt(1 - sig.level / tside, df = n - q - 2),
df = n - q - 2, lambda)
})
}
} else {
if (two.tailed == TRUE) {
pwr.expr <- quote({
lambda <- d * sqrt(p * (1 - p) * n) /
sqrt(1 - r12);
1 - pt(qt(1 - sig.level / tside, df = n - q - 2),
df = n - q - 2, lambda) +
pt(qt(sig.level / tside, df = n - q - 2),
df = n - q - 2, lambda)
})
} else {
pwr.expr <- quote({
lambda <- d * sqrt(p * (1 - p) * n) /
sqrt(1 - r12);
1 - pt(qt(1 - sig.level / tside, df = n - q - 2),
df = n - q - 2, lambda)
})
}
}
limFun <- function(x, y) {
if (!is.null(x) && length(x) == 2 && is.numeric(x)) {x} else {y}
}
nlim <- limFun(x = nlim, y = c(4, 10e10))
powerlim <- limFun(x = powerlim, y = c(1e-10, 1 - 1e-10))
dlim <- limFun(x = dlim, y = c(0, 5))
if(cost.model == TRUE){
if (is.null(power)) {
out <- list(power = eval(pwr.expr))
} else if (is.null(m)) {
ncost <- ((1 - p) * c1 + p * c1t)
mlim <- limFun(x = mlim, y = c(nlim[1] * ncost, nlim[2] * ncost))
out <- list(m = stats::uniroot(function(m)
eval(pwr.expr) - power, mlim)$root)
out <- c(out, list(n = out$m / (((1 - p) * c1
+ p * c1t))))
} else if (is.null(d)) {
out <- list(d = stats::uniroot(function(d)
eval(pwr.expr) - power, dlim)$root)
}
} else {
if (is.null(power)) {
out <- list(power = eval(pwr.expr))
} else if (is.null(n)) {
out <- list(n = stats::uniroot(function(n)
eval(pwr.expr) - power, nlim)$root)
} else if (is.null(d)) {
out <- list(d = stats::uniroot(function(d)
eval(pwr.expr) - power, dlim)$root)
}
}
power.out <- list(funName = funName,
designType = designType,
par = par, out = out)
return(power.out)
}
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