dominant: Example pedigree for linkage analysis

In paramlink: Parametric Linkage and Other Pedigree Analysis in R

Example pedigree for linkage analysis

Description

Medical pedigree with 23 individuals of which 15 are genotyped with 650 SNP markers. Eleven family members are affected by a disease, showing an autosomal dominant inheritance pattern.

Usage

dominant

Format

A data frame with 23 rows and 1306 columns, describing the pedigree and marker data in pre-makeped format. The first 6 columns contain the pedigree structure and affection status, while the final 1300 columns hold the marker alleles.

• FAMID. Family ID

• ID. Individual ID

• FID. Father ID

• MID. Mother ID

• SEX. Gender (male=1, female=2)

• AFF. Affection status (unaffected=1, affected=2, unknown=0)

• M1_1. First allele of marker 1

• M1_2. Second allele of marker 1

• ...

• M650_1. First allele of marker 650

• M650_2. Second allele of marker 650

All markers are SNPs, whose alleles are written as 1 and 2. Missing alleles are denoted by 0.

Examples

x = linkdat(dominant)
summary(x)

paramlink documentation built on April 15, 2022, 9:06 a.m.