Man pages for pleioh2g
Estimation of Pleiotropic Heritability from Genome-Wide Association Studies (GWAS) Summary Statistics

Cal_cor_pleiotropic_h2Compute a vector of pleioh2g for all diseases before...
Cal_cor_pleiotropic_h2_corrected_singleCompute single pleioh2g for target disease after correction...
Cal_cor_pleiotropic_h2_singleCompute single pleioh2g for target disease before correction...
Cal_cor_test_singleCompute inversed elements for the target disease in bias...
Cal_rg_h2g_alltraitsCompute rg + h2g
Cal_rg_h2g_jk_alltraitsgenomic-block jackknife and compute rg + h2g
generate_proposal_sample_changea_corGenerate samples based on sampling covariance matrix and rg...
h2_liabilityConvert Heritability to Liability Scale
h2_vectorh2 vector for 62 traits
h2_vector_math2 jk matrix for 62 traits
ldsc_h2Estimate heritability - refer to ldscr R package...
ldsc_rgEstimate cross-trait genetic correlations (Robust Version) -...
make_weightsInternal Function to make weights - refer to ldscr R package...
merge_sumstatsMerging summary statistics with LD-score files - refer to...
perform_analysisInternal function to perform LDSC heritability/covariance...
pleiotropyh2_cor_computing_singleCompute pleioh2g after bias correction for target disease
pleiotropyh2_cor_computing_single_pruneCompute pleioh2g after bias correction for target disease
pleiotropyh2_nocor_computing_singleCompute pleioh2g before bias correction for target disease
Prune_disease_selection_DTrgzscorePrune disease selection
pruning_pleioh2g_wrapperPerform pruning in computing pleioh2g and correct bias
read_ldRead ld from either internal or external file - refer to...
read_mRead M from either internal or external file - refer to ldscr...
read_sumstatsRead summary statistics from either internal or external file...
read_wldRead wld from either internal or external file - refer to...
Results_full_rgGenetic correlation matrix for 62 traits
Results_full_rg_arrayJackknife array of genetic correlations (62 traits)
Rg_mat_zGenetic correlation Z matrix for 62 traits
sumstats_munged_example_inputExample munged dataframe - refer to ldscr R package...
pleioh2g documentation built on March 9, 2026, 5:07 p.m.