generate_proposal_sample_changea_cor: Generate samples based on sampling covariance matrix and rg...

In pleioh2g: Estimation of Pleiotropic Heritability from Genome-Wide Association Studies (GWAS) Summary Statistics

Generate samples based on sampling covariance matrix and rg matrix for target disease

Description

This function is used to generate samples based on sampling covariance matrix and rg matrix for target disease

Usage

generate_proposal_sample_changea_cor(
  Results_full_rg,
  Results_full_rg_array,
  plei_h2_idx,
  ratio_a
)

Arguments

Results_full_rg	genetic correlation matrix.
Results_full_rg_array	genetic correlation jackknife-block array.
plei_h2_idx	index of the target disease in the rg_mat.
ratio_a	corrected ratio.

Value

noisy_inversed_element for bias correction

Examples

data(Results_full_rg)
data(Results_full_rg_array)
Results_full_rg<-Results_full_rg[1:15,1:15]
Results_full_rg_array<-Results_full_rg_array[1:15,1:15,]
plei_h2_idx<-1
ratio_a <- 0.75
generate_proposal_sample_changea_cor(Results_full_rg,
 Results_full_rg_array, plei_h2_idx, ratio_a)

pleioh2g documentation built on March 9, 2026, 5:07 p.m.