Prune_disease_selection_DTrgzscore: Prune disease selection

In pleioh2g: Estimation of Pleiotropic Heritability from Genome-Wide Association Studies (GWAS) Summary Statistics

Prune disease selection

Description

Prune disease selection

Usage

Prune_disease_selection_DTrgzscore(
  Target_disease,
  trait_name,
  Rg_mat,
  Rg_mat_z,
  rg_threshold
)

Arguments

Target_disease	trait_name of target disease
trait_name	trait_name of pre-prune rg_matrix
Rg_mat	pre-prune rg_matrix
Rg_mat_z	pre-prune rg z matrix
rg_threshold	rg_threshold

Value

Rg_mat_leave

Examples

trait_name<-c("401.1","244.5","318","735.3","411.4",
"427.2","454.1","278.1","250.2","550.1","530.11",
"296.22","519.8","562.1","763")
data("Results_full_rg")
data("Rg_mat_z")
Results_full_rg<-Results_full_rg[1:15,1:15]
Rg_mat_z<-Rg_mat_z[1:15,1:15]
Target_disease<-'401.1'
rg_threshold<-0.3
Rg_prune<-Prune_disease_selection_DTrgzscore(Target_disease, trait_name,
Results_full_rg,Rg_mat_z,rg_threshold)

pleioh2g documentation built on March 9, 2026, 5:07 p.m.