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pmxTools: Pharmacometric and Pharmacokinetic Toolkit
Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).
Getting started
Browse package contents
Package details |
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| Author | Justin Wilkins [aut, cre] (<https://orcid.org/0000-0002-7099-9396>), Bill Denney [aut] (<https://orcid.org/0000-0002-5759-428X>), Rik Schoemaker [aut], Satyaprakash Nayak [ctb], Leonid Gibiansky [ctb], Andrew Hooker [ctb], E. Niclas Jonsson [ctb], Mats O. Karlsson [ctb], John Johnson [ctb] |
| Maintainer | Justin Wilkins <justin.wilkins@occams.com> |
| License | GPL-2 |
| Version | 1.3 |
| URL | https://github.com/kestrel99/pmxTools |
| Package repository | View on CRAN |
| Installation |
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